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Seminar
Mechanical Engineering and Materials Science
Cosponsor: Dean of Engineering
Nanostructure -- Biomolecule Interactions: Implications for Nanomedicine and New Materials
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Richard W. Siegel
Robert W. Hunt Professor of Materials Science and Engineering and
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Rensselaer Polytechnic Institute |
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Wednesday, November 4, 2009
Time: 4:00 PM
to 5:00 PM
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128 Mechanical Engineering Building
Rice University
6100 Main St
Houston, Texas, USA
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Great strides are being made worldwide in our ability to synthesize and assemble nanoscale building blocks to create advanced materials and devices with novel properties and functionalities. Beyond the novel bulk properties of nanostructured materials, nanostructured surfaces have been shown to elicit more favorable and selective biomolecular and cellular responses than surfaces at coarser length scales. These nanoscale attributes are enabling a variety of nanostructures to form the bases for a new field, nanomedicine, as well as for new materials. A fundamental issue in these areas is to understand and eventually control nanostructure-biomolecule interactions. In order to elucidate the bases for observed changes of protein conformation and function on nanostructured surfaces, a number of model experiments are being carried out, the results of which will be presented and discussed in the broader context of tissue regeneration, nanomedicine, and new materials. |
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| speaker bio |
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Dr. Siegel holds degrees from Williams College (AB 1958) and the University of Illinois in Urbana (MS 1960, PhD 1965) and did post-doctoral research at Cornell University before joining the faculty of the Department of Materials Science, State University of New York at Stony Brook (1966-76). He was a research scientist, group leader, and research program manager in the Materials Science Division at Argonne National Laboratory (1974-95). Dr. Siegel was a visiting professor in Germany, Israel, India, Switzerland, and Japan and has been active in many professional organizations. He was a member of the Nanotechnology Technical Advisory Group of the US President’s Council of Advisors on Science and Technology (2003-09), chaired the World Technology Evaluation Center worldwide study on nanostructure science and technology (1996-98), and was past chairman (1992-96) of the International Committee on Nanostructured Materials. He has authored over 260 articles and 15 patents in the areas of defects, diffusion, and nanostructured metal, ceramic, composite, and biomaterials. He has presented more than 470 invited lectures worldwide and edited ten books. Dr. Siegel is a founder and Director of Nanophase Technologies Corporation, and received a 1991 US Federal Laboratory Consortium Award for Excellence in Technology Transfer. He is an Honorary Member of the Materials Research Societies of India and Japan, a recipient of an Alexander von Humboldt Foundation Senior Research Award (1994) in Germany, and a RIKEN Eminent Scientist Award (2001) in Japan. |
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